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Fruit and vegetable intake and mortality from ischaemic heart disease: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heart study.

Low ischaemic heart disease mortality risk is associated with generous intake of fruits and vegetables.

This study investigated the association between high dietary intake of fruits and vegetables and the incidence of deaths from ischaemic heart disease (IHD). Researchers tracked dietary and mortality records of 313,074 men and women without any previous history of myocardial infarction and stroke recruited from 8 different European countries.

The team of investigators discovered that regular consumption of 8 portions (80g per portion) of fruits and vegetables reduce the likelihood of developing fatal ischaemic heart disease by 22%. A 4% reduction in fatal ischaemic heart disease risk was found in subjects who consumed an additional portion of fruits and vegetables. Data from this study suggest that habitual consumption of large servings of fruits and vegetables may decrease the incidence of deaths due to ischaemic heart disease.

Research Summary Information

  • 2011
  • Francesca L. Crowe,, Andrew W. Roddam, Timothy J. Key, Paul N. Appleby, Kim Overvad, Marianne U. Jakobsen, Anne Tjønneland, Louise Hansen, Heiner Boeing, Cornelia Weikert, Jakob Linseisen, Rudolf Kaaks, Antonia Trichopoulou, Gesthimani Misirli, Pagona Lagiou, Carlotta Sacerdote, Valeria Pala, Domenico Palli, Rosario Tumino, Salvatore Panico, H. Bas Bueno-de-Mesquita, Jolanda Boer, Carla H. van Gils, Joline W.J. Beulens, Aurelio Barricarte, Laudina Rodríguez, Nerea Larrañaga, Maria-José Sánchez, María-José Tormo, Genevieve Buckland, Eiliv Lund, Bo Hedblad, Olle Melander, Jan-Håkan Jansson, Patrik Wennberg, Nicholas J. Wareham, Nadia Slimani, Isabelle Romieu, Mazda Jenab, John Danesh, Valentina Gallo, Teresa Norat, Elio Riboli, and European Prospective Investigation into Cancer and Nutrition (EPIC)-Heart Study Collaborators
  • Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7LF, UK Department of Epidemiology, School of Public Health, Aarhus University, Aarhus, Denmark Department of Cardiology, Centre for Cardiovascular Research, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark Department of Clinical Epidemiology, Aarhus University Hospital, Aalborg, Denmark Department of Diet, Cancer, and Health, Institute of Epidemiology, Danish Cancer Society, Copenhagen, Denmark German Institute of Human Nutrition, Nuthetal, Germany German Cancer Research Centre, Division of Cancer Epidemiology, Heidelberg, Germany WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece Unit of Cancer Epidemiology, CPO Piemonte Italy and Human Genetics Foundation, Torino, Italy Department of Preventive and Predictive Medicine, Nutritional Epidemiology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy Molecular and Nutritional Epidemiology Unit, ISPO (Cancer Research and Prevention Institute), Florence, Italy Cancer Registry and Histopathology Unit, ‘Civile M.P. Arezzo' Hospital, Ragusa, Italy Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands Department of Gastroenterology and Hepatology, University Medical Center Utrecht (UMCU), Utrecht, The Netherlands Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands Public Health Institute of Navarra, Pamplona, Spain CIBER en Epidemiología y Salud Pública (CIBERESP), Spain Public Health and Participation Directorate, Health and Health Care Services Council, Asturias, Spain Public Health Department of Gipuzkoa, Basque Government, Spain Andalusian School of Public Health, Granada, Spain Department of Epidemiology, Murcia Regional Health Council, Spain Unit of Nutrition, Environment, and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain Institute of Community Medicine, University of Tromsø, Norway Department of Clinical Sciences, Lund University, Skane University Hospital, Malmö, Sweden Department of Clinical Research, Lund University, Malmö, Sweden Department of Medicine, Skellefteå County Hospital, Skellefteå, Sweden Department of Public Health and Clinical Medicine, Umeå University, Sweden MRC Epidemiology Unit, Addenbrooke's Hospital, Cambridge, UK International Agency for Research on Cancer (IARC-WHO), Lyon, France Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, UK School of Public Health, Imperial College, London, UK *Corresponding author. Tel: +44 1865 289 647, Fax: +44 1865 289 610, Email: ku.ca.xo.uec@eworc.a
  • Yes, Free full text of study was found:
  • No. Potential conflicts disclosure not found
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